CJC-1295 & Ipamorelin 10 mg Blend: Optimal Dosage Guide

Sermorelin, Ipamorelin and CJC-1295 are peptide hormones that work together to stimulate growth hormone secretion, improve sleep quality, increase lean muscle mass, enhance recovery, reduce body fat and boost overall vitality. The most common approach for individuals looking to maximise the benefits of these peptides is a blended protocol that combines 10 mg of Ipamorelin with either sermorelin ipamorelin before and after or CJC-1295 in a single injection. The blend can be administered once or twice daily depending on personal goals, tolerance and the specific peptide used.

CJC-1295 / Ipamorelin (10 mg) Blend Dosage

The 10 mg concentration refers to the total amount of peptides contained in a 1 ml vial, typically formulated as 2.5 mg of each peptide per 0.25 ml. A typical blend for a once-daily injection is:

• CJC-1295 (non-PEGylated) – 5 mg
• Ipamorelin – 5 mg

The total volume injected is usually 1 ml, which can be diluted with sterile water or saline if a smaller dose is desired. For most users the recommended schedule is:

• Morning injection (around 7:00–9:00 AM)
• Optional second injection in the late afternoon (around 4:00–6:00 PM)

When using the non-PEGylated form of CJC-1295, a twice-daily regimen can yield sustained GH peaks throughout the day and night. With the PEGylated variant, a single morning dose is often sufficient because its longer half-life keeps GH levels elevated for 24 hours.

Adjusting the Dose

If you experience excessive sleepiness or swelling at the injection site, consider reducing each peptide to 4 mg (total 8 mg). Conversely, if you are not seeing desired gains in muscle mass or strength after several weeks, an increase to 6 mg of each peptide can be tried. Always adjust gradually and monitor for side effects.

Timing with Food

Peptides work best on an empty stomach because food, especially high-protein meals, can blunt GH release. Take the injection at least one hour before breakfast or two hours after dinner. If you have a late snack, avoid injecting immediately afterward.

HCG Mixing Protocol Calculator

Human chorionic gonadotropin (HCG) is often paired with peptide therapy to support testosterone production and maintain testicular health. A simple calculator can help determine the optimal HCG dose based on body weight and desired testosterone boost. The typical formula is:

HCG Dose (IU) = Body Weight (kg) × 10

For example, a person weighing 80 kg would use 800 IU of HCG per injection. This dose can be divided into two injections daily (400 IU in the morning and 400 IU at night) or given once in the evening. The calculator can also factor in a target testosterone range; if you aim for 700–900 ng/dl, adjust the dose up or down by 200 IU increments.

Practical Steps

1. Weigh yourself on a calibrated scale.
2. Enter your weight into the calculator to receive an IU recommendation.
3. Prepare HCG by reconstituting with sterile water; typical vials contain 500 IU/0.5 ml, so you will need to add the appropriate amount of water to reach the desired concentration.
4. Mix thoroughly, then aliquot into syringes for daily use.

Always keep a log of your HCG doses and testosterone levels (if monitored) to fine-tune the protocol over time.

Search

When researching peptide protocols, it is important to consult multiple reputable sources such as peer-reviewed journals, professional societies in endocrinology and anti-aging medicine, as well as established peptide manufacturers. Use targeted search terms like “CJC-1295 Ipamorelin blend dosage,” “non-PEGylated CJC-1295 protocol” or “HCG dose calculator for testosterone support.” Compare the results from clinical studies that measured growth hormone secretion patterns, body composition changes and safety outcomes. Cross-reference user forums and professional discussion boards for anecdotal evidence while keeping in mind that individual responses can vary widely.

In summary, a balanced approach using a 10 mg blend of CJC-1295 or Sermorelin with Ipamorelin, paired with an HCG dose calculated from body weight, provides a robust foundation for maximizing growth hormone stimulation and maintaining hormonal equilibrium. Adjustments should be made cautiously, monitoring both subjective improvements and objective lab values to ensure optimal results.